Malaria Treatment FAQ:
I just read an article out of national geographic magazine from july 2007. Part of the article talks about how Stephen Hoffman and the Sanaria company are developing a vaccine with falciparum infected parasites from adult female mosquitoes, to create a vaccination against malaria. They weaken the parasites with with a quick dose of radiation, before packing them into a hypodermic needle. Now, would this type of vaccine be a killed type, attenuated or acellular vaccine?
I just read an article out of national geographic magazine from july 2007. Part of the article talks about how Stephen Hoffman and the Sanaria company are developing a vaccine with falciparum infected parasites from adult female mosquitoes, to create a vaccination against malaria. They weaken the parasites with with a quick dose of radiation, before packing them into a hypodermic needle. Now, would this type of vaccine be a killed type, attenuated or acellular vaccine?






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Finally, an intelligent question on vaccines! I have been thinking about that very same question on the vaccine that Steve Hoffman is working on for malaria and my only conclusion is that it will have to be registered as a modified live (attenuated) vaccine. I had even checked with someone in the FDA and they were not certain how it would be registered yet either. I think they will have a problem scaling this product though.
Good question.