Malaria Treatment FAQ:
Once someone has been diagnosed and treated for Falciparum Malaria what can be the possible long term effects on organs, eye sight etc.
Once someone has been diagnosed and treated for Falciparum Malaria what can be the possible long term effects on organs, eye sight etc.






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Depending on how early the treatment started and if there were any complications already, it really depends. In most cases of malaria, outlook with treatment is good, but with p. falciparum, especially if there are already complications, it can be bad. Sorry hun, I was not able to find numbers.
P. falciparum of all the 4 protozoa that can cause malaria has the worst mortality and morbidity.
In malaria in general, protozoa replicate in the red blood cells and eventually causes them to break open, releasing compounds many of which are toxic. The person appears to be experiencing a flu with: discomfort, muscle aches, headache, and chills - symtpoms which generally come in cycles. Those with malaria can also become jaundiced and anemic.
P. falciparum is the worst of the 4 protozoa b/c:
- unlike the other protozoa, it is not restricted to infecting red blood cells of any specific level of maturity/age - leaving it more open to infect many more cells
- it is very powerful at adhering to cells. When a red blood cell is infected with it, knobs of protein are made which bind to cells of the blood vessel walls (endothelial cells). Many of these red blood cells start to clump together, often occluding blood flow.
The last point, occluding blood flow is mainly what leads to the complications associated with p. falciparum:
- renal problems (including kidney failure)
- coma
- cerebral infection
- pulmonary edema
- RAPID onset anemia
- liver failure
- meningitis
- breakdown of massive numbers of red blood cells aka hemolytic anemia
- spleen rupture with subsequent massive hemorrhage
- death
Of course, complications and prognosis are assessed case by case, especially with regards to other conditions may also be present, when and what treatments where given.
Hope that helps!